Dr. apt. Dian Ayu Eka Pitaloka, M.Si

SHORT BIOGRAPHY

Name : Dian Ayu Eka Pitaloka
Born in : Jember, January 11, 1993
Nationality : Indonesian
Gender : Female
Job Title : Lecturer/researcher
Work Place : Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran – Indonesia
Email : pitaloka@unpad.ac.id

EDUCATIONAL BACKGROUND

Degree	Year	University
Bachelor	2010 – 2014	Universitas Jember – Indonesia
Professional (Pharmacist)	2014 – 2015	Institut Teknologi Bandung – Indonesia
Master	2015 – 2017	Institut Teknologi Bandung – Indonesia
PhD	2017 – 2020	Institut Teknologi Bandung – Indonesia

RESEARCH INTEREST

Biomedical data science and bioinformatics of infectious diseases, with a focus on biomarker findings in tuberculosis.

RESEARCH EXPERIENCE

Year	Research Title	Program
2023	Exploration of the Inhibition of Triterpenoid and Limonoid Compounds Against Mycobacterium Tuberculosis using the Microscopic Observation Drug Susceptibility (MODS) Method	UNPAD internal research grant
2023	Cell-based biosensor for diagnosis of urine mycobacteria lipoarabinomannan: recent advancement and challenges	UNPAD internal research grant
2023	In silico study of triterpenoid and limonoid derivatives as enoyl acyl carrier protein reductase (inha) enzyme inhibitors of Mycobacterium tuberculosis	UNPAD internal research grant
2022	Determination of critical concentrations of second-line antituberculosis drugs for Mycobacterium tuberculosis susceptibility testing using the MycoTB sensititre	UNPAD internal research grant
2017	Antituberculosis action of ursolic acid and its regulation in C57BL/6 mouse bone marrow macrophages infectd with Mycobacterium avium	Dikti-funded research grant

RESEARCH PUBLICATION

Scopus ID: 571938483000 (h-index 7, total citations of 110 by 103 documents, per December, 2023)

Year	Document Title	Journal
2023	Development and validation of assessment instrument for the perception and attitude toward tuberculosis among the general population in Indonesia: a Rasch analysis of psychometric properties	Frontiers in Public Health, 2023, 11, 1143120
2023	Discovery of potent triterpenoid and limonoid compounds targeting Mycobacterium tuberculosis enoyl acyl carrier protein reductase (InhA): An in silico investigation	Informatics in Medicine Unlocked, 2023, 40, 101299
2023	Insights from the molecular mechanism of pyrazinamide to mutated pyrazinamidase linked to the pncA gene in clinical isolates of Mycobacterium tuberculosis	Journal of Biomolecular Structure and Dynamics, 2023
2022	Transcriptional biomarkers for treatment monitoring of pulmonary drug-resistant tuberculosis: Protocol for a prospective observational study in Indonesia	Tropical Medicine and Infectious Disease, 2022, 7(11), 326
2022	Rasch Modelling to Assess Psychometric Validation of the Knowledge about Tuberculosis Questionnaire (KATUB-Q) for the General Population in Indonesia	International Journal of Environmental Research and Public Health, 2022, 19(24), 16753
2022	Multi Epitope-Based Vaccine Design for Protection Against Mycobacterium tuberculosis and SARS-CoV-2 Coinfection	Advances and Applications in Bioinformatics and Chemistry, 2022, 15, pp. 43–57
2021	Omics biomarker for monitoring tuberculosis treatment: A mini review of recent insights and future approaches	Infection and Drug Resistance, 2022, 15, pp. 2703–2711
2021	Docking-based virtual screening and molecular dynamics simulations of quercetin analogs as enoyl-acyl carrier protein reductase (Inha) inhibitors of mycobacterium tuberculosis	Scientia Pharmaceutica, 2021, 89(2),20
2020	Regulation of mitogen-activated protein kinase signaling pathway and proinflammatory cytokines by ursolic acid in murine macrophages infected with Mycobacterium avium	Infectious Disease Reports, 2020, 12, 8717

WORK EXPERIENCE

Year	Job Title	Job Description	Organization
2021-current	Lecturer	Research of interest: · Biomarker findings in tuberculosis treatment using omics analysis · Develop a digital health system using biomedical data on infectious diseases	Department of Pharmacology-Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran
2023	Visiting research staff	Training on next-generation sequencing using nanopore and downstream analysis using omics data	Bioinformatics Center, Department of Infection Metagenomic, Osaka University, Japan
2020-2021	Postdoctoral Fellow	Conducted research on: · Screening and validation of blood-based signature in tuberculosis treatment · Genotypic-phenotypic correlation of pyrazinamide resistant in multidrug-resistant TB	Department of Pharmacology-Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran
2020	Research analyst	· Conducted regular testing for COVID-19 using real-time PCR · Performed research on the validation of rapid diagnostic tests for COVID-19	Central Laboratory Universitas Padjadjaran
2018-2019	Visiting research scientist	Performed research on understanding the regulation of the MAPK signalling pathway by ursolic acid in macrophages infected with Mycobacteria	Department of Respiratory Sciences, University of Leicester, United Kingdom

COMMUNITY SERVICE EXPERIENCE

Year	Job Title	Program Title	Location
2023	Educator	Pharmacamp 2023: Assisted village of tropical fruit from Parakanmanggu for Indonesia	Pangandaran – Indonesia
2023	Educator	Education of antibacterial solid soap making based on manggis skin and virgin coconut oil in Parakanmanggu village	Pangandaran – Indonesia
2022	Educator	Education of antibiotic resistance in children for parents in Arcamanik District	Bandung – Indonesia

ORGANIZATION EXPERIENCE

Year	Position	Organization
2021 – current	Member	Jejaring Riset Tuberculosis (JetSet TB)
2023 – current	Member	Super Photon ring-8 GeV (SPRING-8)
2016 – current	Member	Indonesian Pharmacist Association (IAI)