Upon completion of this course, students are expected to be able to:

1.        Explain various factors involved in design, production and evaluation of multiple drug dosage forms and other drug delivery system

2.        Present the ability to interpret and analyze data

3.        Design, produce and evaluate drug dosage forms and other drug delivery system

4.        Characterize and evaluate the psychochemical properties of pharmaceutical ingredients

5.        Show contributions both in individual or group project

6.        Summarize the information collected from the group and communicate the development of the topic

●         Lecture

●         Discussion

●         Audio visual Learning

●         Presentation

●         Discussion

●         Quiz

1. Dengale, S.J., Grohganz, H., Rades, T., L¨obmann, K., 2016. Recent advances in co- amorphous drug formulations. Adv. Drug Deliv. Rev. 100, 116–125. https://doi.org/ 10.1016/j.addr.2015.12.009.
2. Dengale, S.J., Ranjan, O.P., Hussen, S.S., Krishna, B.S.M., Musmade, P.B., Gautham Shenoy, G., Bhat, K., 2014. Preparation and characterization of co-amorphous ritonavir-indomethacin systems by solvent evaporation technique: Improved dissolution behavior and physical stability without evidence of intermolecular interactions. Eur. J. Pharm. Sci. 62, 57–64. https://doi.org/10.1016/j. ejps.2014.05.015.
3. Dening, T.J., Taylor, L.S., 2018. Supersaturation potential of ordered mesoporous silica delivery systems. Part 1: Dissolution performance and drug membrane transport rates. Mol. Pharm. 15, 3489–3501. https://doi.org/10.1021/acs. molpharmaceut.8b00488.
4. Dening, T.J., Zemlyanov, D., Taylor, L.S., 2019. Application of an adsorption isotherm to explain incomplete drug release from ordered mesoporous silica materials under supersaturating conditions. J. Control. Release 307, 186–199. https://doi.org/ 10.1016/j.jconrel.2019.06.028.
5. Skorupska, E., Jeziorna, A., Potrzebowski, M.J., 2016. Thermal solvent-free method of loading of pharmaceutical cocrystals into the pores of silica particles: A case of naproxen/picolinamide cocrystal. J. Phys. Chem. C 120, 13169–13180. https://doi. org/10.1021/acs.jpcc.6b05302.
6. Skorupska, E., Ka´zmierski, S., Potrzebowski, M.J., 2017. Solid state NMR characterization of ibuprofen:nicotinamide cocrystals and new idea for controlling release of drugs embedded into mesoporous silica particles. Mol. Pharm. 14, 1800–1810. https://doi.org/10.1021/acs.molpharmaceut.7b00092.
7. Skorupska, E., Paluch, P., Jeziorna, A., Potrzebowski, M.J., 2015. NMR study of BA/FBA cocrystal confined within mesoporous silica nanoparticles employing thermal solid phase transformation. J. Phys. Chem. C 119, 8652–8661. https://doi.org/10.1021/ jp5123008.
8. Zhao Z, Katai H, Higashi K, Ueda K, Kawakami K, Moribe K. Cryo-TEM and AFM observation of the time-dependent evolution of amorphous probucol nanoparticles formed by the aqueous dispersion of ternary solid dispersions. Molecular pharmaceutics. 2019 Mar 29;16(5):2184-98.
9. Sunazuka Y, Ueda K, Higashi K, Tanaka Y, Moribe K. Combined effects of the drug distribution and mucus diffusion properties of self-microemulsifying drug delivery systems on the oral absorption of fenofibrate. International journal of pharmaceutics. 2018 Jul 30;546(1-2):263-71.