P20.02011 – Faculty of Pharmacy, Universitas Padjadjaran

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P20.02011

Pharmacogenomics

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Course Information

Course Semester Plan

Course Information

No	Module name	Pharmacogenomics
1	Courses code	P20.02011
2	Study loads	2 credits
3	Semester	Second Semester
4	Precondition	there is no
5	Competence	Upon completion of this course, students are expected to be able to: 1. List and explain the psychochemical properties of solute and solvent that affect solubility, stability, and other biopharmaceutical properties used in the development of pharmaceutical & biopharmaceutical dosage forms, traditional medicines & supplements, and cosmetics 2. Show contributions in individual or group projects. 3. Summarize information and communicate its development obtained from group experience
6	Elements of competency	MKK
7	Type competency	supporting competence
8	Syllabus	1-2. Introduction to Pharmacogenomics and pharmacogenetics, as well as genotyping methods; 3-5. Pharmacogenetics and race / ethnicity, pharmacogenetic Adverse Drug Reactions, Potential of social, ethical, and legal issues of pharmacogenetic development; 6-7. Pharmacogenetics and oncology, pharmacogenetics and infectious diseases; 8. Mid-term exam; 9-10. Polymorphisms in the treatment of cardiovascular and respiratory diseases, pharmacogenetics and metabolic diseases; 11-14. Pharmacogenomics of human p-glycoproteins, drug transporters, drug metabolizing enzymes, and drug targeting enzymes; 15. Case study discussion: Pharmacogenomic contribution to drug therapy: Warfarin, Clopidogrel,: Irinotecan, Aspirin etc; 16. Final Exam
9	Attribute to soft skills	Creativity in discussions, making resumes, presentations, discipline in submitting assignments
10	Learning methods	Lectures and Discussion
11	Learning media	the LCD viewer, lapto p, white board and “online” (Google Meet)
12	Appraisal	Presentation, Midterm Exam, and Final Exam
13	Lecturer	Apt. Melisa Intan Barliana, Dr.Med.Sc.. Dr. Apt. Tina Rostinawati, M.Si., and Apt, Taofik Rosdiana, Ph.D.
14	References	Pharmacogenomics in Ethnobridging and Pharmacovigilance,Editor(s): Y. W. Francis Lam, Stuart A. Scott,Pharmacogenomics (Second Edition), Academic Press, 2019, Pages 289-327, ISBN 9780128126264,https://doi.org/10.1016/B978-0-12-812626-4.00011-5. (https://www.sciencedirect.com/science/article/pii/B9780128126264000115) Keywords: Data applicability; Ethnicity; Ethnobridging; Genetic gradients; Global drug development; Pharmacogenomics; Pharmacovigilance; Variability in drug response Bertino J.S., Jr, & DeVane C, & Fuhr U, & Kashuba A.D., & Ma J.D.(Eds.), (2013). Pharmacogenomics: An Introduction and Clinical Perspective. McGraw Hill. https://accesspharmacy.mhmedical.com/content.aspx?bookid=511&sectionid=40849364 Fleeman, N., Martín Saborido, C., Payne, K., Boland, A., Dickson, R., Dundar, Y., … & Walley, T. (2011). The clinical effectiveness and cost-effectiveness of genotyping for CYP2D6 for the management of women with breast cancer treated with tamoxifen: a systematic review Aniel W. Nebert, Ge Zhang,16 – Pharmacogenomics,Editor(s): Reed E. Pyeritz, Bruce R. Korf, Wayne W. Grody,Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics (Seventh Edition),Academic Press,2019,Pages 445-486. Pratt, V. M., McLeod, H. L., Rubinstein, W. S., Scott, S. A., Dean, L. C., Kattman, B. L., & Malheiro, A. J. (2012). Medical genetics summaries [https://pubmed.ncbi.nlm.nih.gov/28520340/]

Course Semester Plan

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