Course Information
Course Semester Plan
Course Information
| No | Module name | Drug Synthesis & Therapeutic Evaluation |
| 1 | Courses code | P20.02026 |
| 2 | Study loads | 2 credits |
| 3 | Semester | Second Semester |
| 4 | Precondition | there is no |
| 5 | Competence | Upon completion of this course, students are expected to be able to: 1. List and explain the psychochemical properties of solute and solvent that affect solubility, stability, and other bio- pharmaceutical properties in drug dosage forms development. 2. Present the ability to interpret and analyze data. 3. Develop, validate and apply different instrumental analytical technique in drug analysis on various drug dosage forms. 4. Characterize and evaluate physicochemical properties of pharmaceutical ingredients. 5. Show contributions both in individual or group project. |
| 6 | Elements of competency | MKK |
| 7 | Type competency | supporting competence |
| 8 | Syllabus | 1. Introduction and Organic Chemical Synthesis Experiments at Micro Scale; 2. Role of Drug Synthesis and Therapeutic Testing in Drug Discovery; 3-4. Introduction to Drug Synthesis and its Therapeutic Testing Methods; 5. Purification, Isolation, and Characterization; 6-7. Drugs Synthesis and Therapeutic Testing : Narcotics and Psychotropic; 8. Mid-Term Exam; 9-10. Drug Synthesis and Therapeutic Testing : antipyretic analgesics, anti-inflammatory; 11-15. Drug Synthesis and Therapeutic Testing: Antivirals, Antibiotics and Sulfonamides, Antidiabetics, Cardiac and Anticancer Drugs. 16. Final Exam |
| 9 | Attribute to soft skills | communication skill, discipline, ethics, awareness |
| 10 | Learning methods | Lectures and Discussions, Journal Resume Presentation |
| 11 | Learning media | LCD |
| 12 | Appraisal | Presentation score, resume assignment and written test |
| 13 | Lecturer | Dr. Apt. Ida Musfiroh, M.Si. and Dr. Apt. Sandra Megantara, M.Farm. |
| 14 | References | Carstensen, Jens T., et al, Drug Stability : Principles and practices, Marcel Dekker, 2000 Yoshioka, Sumie and Stella, Valentino J., Stability of Drugs and Dosage forms, Kluwer academic, 2002 Tonnesen, Hanne H., Photostability of Drugs and Drug Formulations, CRC Press, 2004 Aulton, Michael E., Pharmaceutics : The Science of Dosage Form Design, W.B. Saunders Company, 2003 Piechocki, Joseph T., and Thoma, Karl, Pharmaceutical Photostability and Stabilization Technology, Informa Health, 2007.Kim Huynh-Ba, Handbook of Stability Testing in Pharmaceutical Development : Regulations, Methodologies and Best Practices, Springer Science, 2009 Brittain, Harry G., Polymorphism in Pharmaceutical Solids, Informa Health, 2009. Sinko, Patrick J., and Singh Yashveer, Martin’s Physical Pharmacy and Pharmaceutical Sciences : Physical Chemical and Biopharmaceutical Principles in the Pharmaceutical Sciences, Wolters Kluwer, 2011 Loftsson, Thorsteinn, Drug Stability for Pharmaceutical Scientists, Elsevier, 2014 |
Course Semester Plan