Course Information
Course Semester Plan
Course Information
| 1 | Module name | Natural Product Compound Separation Methods |
| 2 | Courses code | P20.02018 |
| 3 | Study loads | 2 credits |
| 4 | Semester | Second Semester |
| 5 | Precondition | there is no |
| 6 | Competence | Upon completion of this course, students are expected to be able to: 1. Explain the psychochemical properties of chemical compound that affect solubility, stability, and other bio- pharmaceutical properties in drug dosage forms development of herbal medicine 2. Characterize and evaluate the psychochemical properties of natural ingredients 3. Apply various separation technique from natural compound to isolate active compound and marker 4. how contributions both in individual or group project 5. Summarize the information collected from the group and communicate the development of the topic |
| 7 | Elements of competency | MKK |
| 8 | Type competency | Supporting competence |
| 9 | Syllabus | 1. Separation methods of natural compounds; 2. Separation method; 3. Extraction; 4. Chromatography principles; 5. Gas chromatography; 6. Flat liquid chromatography; 7. Conventional liquid chromatography; 8. Mid-term Exam; 9. High pressure liquid chromatography; 10. Size exclusion chromatography; 11. Ion exchange chromatography, ion affinity chromatography; 12. Countercurrent liquid chromatography; 13. Preparative liquid chromatography, electrophoresis: 14-15. Individual/group assignment; 16. Final Exam |
| 10 | Attribute to soft skills | communication skill, ethics, discipline |
| 11 | Learning methods | Lecture. Presentation, and Discussion |
| 12 | Learning media | LCD/projector, White board and Hand out |
| 13 | Appraisal | Quiz, Assignment, Mid-Term Exam, and Final Exam |
| 14 | Lecturer | Dr. Apt. Yoppi Iskandar, M.Si. and Dr. Apt. Ade Zuhrotun, M.Si. |
| 15 | References | Shah B & Seth AK. 2020. Textbook of Pharmacognosy and Phytochemistry, 2nd Ed. CBS Publisher & Distributor. India. Heinrich M, Barnes J, Gibbons S, Williamson EM. 2012. Fundamentals of Pharmacognosy and Phytochemistry. Elsevier Churchill Livingstone. UK. Watson RR. 2018. Polyphenols in Plants: Isolation, Purification and Extract Preparation. Elsevier Science. Sarker SD, Nahar L. 2012. Natural Products Isolation. Humana Press Springer Protocols. Sicker D, Zeller KP, Siehl HU, Berger S. 2019. Natural Products: Isolation, Structure Elucidation, History. Willey-VCH. Darcy C Burns, William F Reynolds, 2018, Optimizing NMR Methods for Structure Elucidation: Characterizing Natural Products and Other Organic Compounds, Royal Society of Chemistry, London. Maria Magdalena, Jorge Bravo, 2015, Structure Elucidation in Organic Chemistry: The Search for the Right Tools, Wiley-VCH, New York. |
Course Semester Plan