Prof. Dr. apt. Anas Subarnas, M.Sc

A. PERSONAL

Name	:	Prof. Dr. Anas Subarnas, M.Sc.
Date & place of birth	:	19 July, 1952, Ciamis
Affiliation	:	Faculty of Pharmacy, Universitas Padjadjaran
Address	:	Jl. Anggrek Raya 03, Rancaekek Kencana, Rancaekek, Bandung
Email address	:	a.subarnas@unpad.ac.id/aasubarnas@yahoo.co.id
Position	:	Chairman of the Senate of the Faculty of Pharmacy
Expertise	:	Pharmacology and Clinical Pharmacy

B. Education

1972 – 1982	: Undergraduate Course of Pharmacy, Universitas Padjadjaran
1987 – 1989	: Master Course, Pharmaceutical Institute, Tohoku University, Japan
1990 – 1993	: Doctor Course, Pharmaceutical Institute, Tohoku University, Japan

C. Organisation

Indonesian Pharmacist Association (1993 – Now)
Academic Senate of Universitas Padjadjaran (2015 – Now)

D. Research & Research Grant (in the last 5 years)

No.	Title	Year	Research Funder
1.	Discovery of bioactive compounds and development of herbal medcines having therapeutic potency for infected virus diseases untuk penyakit infeksi virus, kanker servik, dan metabolic syndrome.	2015 – 2020	– Academic Leadership Grant(ALG), Unpad
2. 3. 4. 5. 6. 7. 8. 9.	Modification of chalcone compound isolated from Eugenia aquea leaves as novel therapeutic compounds targeted on breast cancer Evaluation of antiproliferation and mechanism of action of the caffeic acid phenethyl ester, -5 Fluorouracil, and propolis combination on breast cancer cells Examination of analgesic and antinflammatory mechanism of action of the extract and proanthocyanidin of Polypodium feei roots through inhibition of inflammatory mediators on RAW264.7 cells Optimation and formulation of solid dispersion of apigenin by the method of hot melt extrusion (HME) as anticalculi Formulation, characterization, and toxicity test of ophthalmic gel preparation in situ Formulation, characterization, and optimalization of ophthalmic gel preparation in situ for eye’s infection treatment Preparation and development of standardized herbal medicine of Polypodium feei extract for managment of pain Discovery of new anticancer candidates of Indonesian toxic plants	2016 – 2017 2019-2020 2019-2020 2019 -2020 2019 – 2020 2019 – 2020 2019 2019 – 2020	The Ministry of Research & Technology and Higher Education of Indonesia The Ministry of Research & Technology and Higher Education of Indonesia The Ministry of Research & Technology and Higher Education of Indonesia The Ministry of Research & Technology and Higher Education of Indonesia The Ministry of Research & Technology and Higher Education of Indonesia The Ministry of Research & Technology and Higher Education of Indonesia The Ministry of Health of Indonesia The Ministry of Research & Technology and Higher Education of Indonesia

E. Community Service

No.

Title

Year

Place

Funder/IDR

Empowering the potential of family medicinal plants to improve the health of rural community

Health education for teeth, mouth, and kidneys and the use of herbal medicine for health

Development of herbal medicinal products that have potential for anti-cancer, anti-infection and anti-calculi therapeutics

2016

2017

2018

Mekarsari and Jatisura villages, Jatiwangi sub-district of Majalengka district
Cikoneng village, Cikoneng sub-district of Ciamis district
Langensari village, Solokanjeruk sub-district of Bandung district

Unpad

Sosialization and education of teeth, mouth, and kidney health cares as well as prevention of viral infections based on anti covid-19 health protocols

2019

Cinunuk village, Cileunyi sub-district of Bandung district

Unpad

F. Publications in the last 5 years (H-index: 16 (Scholar), 11 (Scopus))

International Journal

Tittle

Journal

Year

Quartiles

Analysis of chemical composition and its analgesic and anti-inflammatory activity of essential oil of sintoc bark (Cinnamomum sintoc bl.) using in vivo method,A study to predict anti-inflammatory of eugenol, myristicin, and limonene of Cinnamomum sintoc

Discovering COX-inhibitors in volatile oil of Cinnamomum sintoc,

Apoptosis-mediated antiproliferative activity of friedolanostane triterpenoid isolated from the leaves of Garcinia celebica against MCF-7 human breast cancer cell linesHair growth potential of combination of celery (Apium graveolens L.) and mangkokan (Nothopanax scutellariumMerr) leaf extracts on male white rabbits.
Antibacterial properties of selected plants consumed by primates against Escherichia coli and Bacillus subtilis.Inhibition of Phosphorylated c‑Jun NH(2)‑terminal Kinase by 2’,4’‑dihydroxy‑6‑methoxy‑3,5‑ dimethylchalcone Isolated from Eugenia aquea Burm f. Leaves in Jurkat T‑cellsMolecular docking and 3D pharmacophore modeling to study the interaction of chalcone derivatives with estrogen receptor alpha,Catechin isolated from Garcinia celebica leaves inhibit plasmodium falciparum growth through the induction of oxidative streesValidation of UV-VIS spectrophotometry method for analysis of apigenin in celery extract (Apium graveolens L)Development of temulawak starch(Curcuma xanthorrhiza Roxb) as potential basic materials in face powders, International Journal ofHepatoprotective and antioxidant activity of the ethanol extract of Cassia fistula L.
Essential oil components of leaves and rhizome of Zingiber ottensii Val. From Bandung, Indonesia,In vitro antiplasmodium activity of Dysoxylum caulostachyum (Miq) and Garcinia celebica (L) leaf extracts against Plasmodium falciparum
M Muchtaridi, FS Afiranti, PW Puspasari, A Subarnas, Y Susilawati. 2018. Cytotoxicity of Garcinia mangostana L. pericarp extract, fraction, and isolate on HeLa cervical cancer cells
Triyono, T., Chaerunisaa, A,Y., Subarnas, A. 2018. Antioxidant activity of combination of ethanol extract of turmeric rhizome and ethanol extract of trengguli bark with DPPH method.Irna Sufiawati, Indra Gunawan, Indra Wijaya, Taofik Rusdiana, Anas Subarnas. 2018. Reduction of salivary tumor necrosis factor alpha levels in response to magic mouthwash with curcuma xanthorriza in cancer patients undergoing chemotherapyStiani, S.N., Rusdiana, T. and Subarnas, A. 2018. Enhancing Dissolution and Bioavaibility of Purely Water Insoluble Natural Compounds by Solid Dispersion with Hot Melt Extrusion TechniqueTina, R., Subarnas, A. and Ekawati R. N. Amplification of Gene Encoding 16s RNA and Antibiotic Resistance Testing for Bacteria causing Upper Respiratory Tract Infection Pneumonia in Patient Sputum Sample.Keri Lestari, Ajeng Diantini, Melisa I. Berliana, Tri H. Ahmad, Anas Subarnas, Mutakin, Rizky Abdulah, Ronny Lesmana, and Jae K. Hwang. 2019. Potential natural dual agonist PPARα/γ-induced antidiabetic and antidislipidemic properties of safrole-free nutmed seed (Myristica fragrans Houtt) extract.Maulana Yusuf Alkandahri, Afiat Berbudi, Novi Vicahyani Utami, Anas Subarnas. Antimalarial activity of extract and fractions of Castanopsis costata (Blume) A.DC.Eri Amalia, Ajeng Diantini, Anas Subarnas. 2019. Overview of current and future targets of breast cancer medicines.Muchtaridi M, Yusuf M, Syahidah HN, Subarnas A, Zamri A, Bryant SD, Langer T. Cytotoxicity of Chalcone Of Eugenia aquea Burm F. Leaves Against T47D Breast Cancer Cell Lines and Its Prediction as an Estrogen Receptor Antagonist Based on Pharmacophore-Molecular Dynamics Simulation.Physical study of Chloramphenicol In Situ Gel with Base Hydroxypropyl Methylcellulose and Poloxamer 188,
Utilization of Poloxamer as Well as Combinations with Other Polymers as Base in Ophthalmic in Situ Gel Dosage FormAntimalarial activity of extract and fractions of Trifolia (L.) Domin,

Apoptosis‐mediated antiproliferation of A549 lung cancer cells mediated by Eugenia aquea leaf compound 2′,4’‐dihydroxy‐6’‐methoxy‐3′,5’‐dimethylchalcone and its molecular interaction with caspase receptor in molecular docking simulation,Antibacterial activity and subchronic toxicity of Cassia fistula L. barks in rats
Inclusion of biopiperine in the kappa-carrageenan complex might improve its bioaccessibility and in vivo anti-inflammatory activity in edema-induced Wistar rats
Activity and Effectiveness of Recombinant hEGF Excreted by Escherichia coli BL21 on Wound Healing in Induced Diabetic Mice,

Water‐soluble propolis and bee pollen of Trigona spp. from South Sulawesi Indonesia induce apoptosis in the human breast cancer MCF‐7 cell line
In situ ophthalmic gel forming systems of poloxamer 407 and hydroxypropyl methyl cellulose mixtures for sustained ocular delivery of chloramphenicole: optimization study by factorial design,
The Use of Various Polymers with Solid Dispersion Application of Hot Melt Extrusion (HME) Preparing New Delivery Drug System
Implementation of Mobile Application for Diabetes Self-Management on Self Efficacy and Clinical Outcome in Indonesia

Collaboration Between Interprofessio-nal Healthcare and Patients to Improve Quality of Life Type 2 Diabetes via Smartphone Application

Applied Pharmaceutical Science 5(02), 058-065.
International Journal of Pharmacy and Pharmaceutical Sciences, vol. 7,issue 12International Journal of Pharmacy and Pharmaceutical Sciences, vol. 7,issue 12Biomedical Reports 4: 79-82.

International Journal of Current Medical Sciences, Vol. 6, Issue, 11, pp. 188-195.Southeast Asian J Trop Med Public Health, Vol 48 No. 1.Pharmacognosy Magazine, vol 13, issue 51, (supplement 3), 5573
Pharmaceuticals 10 (4), 81.

Pharmacognosy magazine 13 (Suppl 2), S301
Pharmaciana 7 (2), 159-168.

Current Medical Sciences, vol 10 (1), 387-391.Barks, Pharm. Sci. & Res. Vol. 10(6), 1415-1417Res J Chem Environ 22.
Journal of Pharmaceutical Sciences and Research 10 (2), 391-393Journal of Pharmaceutical Sciences and Research 10 (2), 348-351
Indonesian Journal of Pharmaceutical Science and Technology 5 (2), 43-48Journal of Research in Pharmacy , 22(3). 1-5.

Journal of Global Pharma Technology, ISSN: 0975 -8542, 139-151.
Res. J. Chem. Environ.Vol. 22 (3), 12-15.

The Natural Products Journal, 9, 1-6.

Avicenna Journal of Phytomedicine. Vol 9, 1-8.

J. Pharm. Sci. & Res. Vol. 11(6), 2385-2397.Advances and Aplications in Bioinformatics and Chemistry, vol 12, 33-43.

Journal of Pharmacy and Bioallied Sciences, Vol 11, Suppl 4,547-550IJDDT, Volume 10 Issue 1, 101-105.

International Journal of Pharmaceutical Research, Suppl Issue 1, 1435-1441.Oncology Letters 19: 3551-3557.

Toxicology Reports, 7 (2020) 649–657.
Journal of Applied Pharmaceutical Science Vol. 10(06), 039-043.

Journal of Experimental Pharmacology, 12, 339-348
Oncology letters 20: 274.

Heliyon, 6, 3-9.

Journal of Global Pharma Tech, 105-122, Available Online at: www.jgpt.co.in
International Journal of Pharmaceutical Research, Vol 12, Suppl Issue 2, 1890-1896.
International Journal of Pharmaceutical Research, Vol 13, Issue 1, 645-650

2015

2016

2017

2018

2019

2020

√

National Accreditation Journal

Tittle

Journal

Year

Sinta

S1-S2

S3-S4

S5-S5

Application of ion-exchange resin column for basic development of strontium-90/Yttrium-90 generator for preparation of radiopharmaceutical therapy
Aktivitas antimalaria daun Erythrina variegate,
Sofian1, F.F., Tjitraresmi, A., Runadi, D., Kania, Y.R. and Subarnas, A. 2018. Brine shrimp lethality bioassay and phytochemical screening of primates-consumed plants from Pangandaran Beach Conservation Area,
Dani Sujana, Deden Winda Suwandi, Taofik Rusdiana, Anas Subarnas. Acute toxicity test of ethanol extract of pakis tangkur (Polypodium feei meet) root from talaga bodas mountain on swiss webster mice,

Indonesian Journal of Chemistry 17 (1), 15-21

Jurnal Natur Indonesia 10 (1), 36-41
ISPST, ISSN: 0975-1459, 79-85.

Jurnal Ilmiah Farmako Bahari, Vol. 11; No. 2, 167-179.

2017

2018

2020

√

G. SCIENTIFIC MEETINGS AS A SPEAKER IN THE LAST 5 YEARS

Seminar/Symposium

Place

Year

Position

Invited

Oral

Poster

Research and development of herbal medicine from upstream to downstream

The Second International Seminar and Expo of Jamu
Workshop: Review on research proposal
National seminar on development of natural products in therapy of asmathic disease
11^th Mulawarman Pharmaceutical Conferences (11^th MPC)
Guest lecture on pharmacology

Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Garut University, Garut
Universitas Padjadjaran, Bandung
Poltikes, Tasik-malaya
The Higher School of Health Sciences, Bakti Nusa Husada, Tasikmalaya
University of Mulawarman,Samarida, Kalimantan
Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Tadulako University, Sulawesi

2015

2017

2018

2020

√

H. REVIEWER/EDITOR

a. Scientific Journal
No	Position and Journal	Year
1	Reviewer, Journal of Applied Pharmaceutical Science	2017- Now
2	Reviewer, SPANDIDOS PUBLICATION: International Journal of Oncology	2016- Now
3	Reviewer, SPANDIDOS PUBLICATION: Oncology Letters	2016- Now
4 5	Reviewer, SPANDIDOS PUBLICATION: International Journal of Molecular MedicineReviewer, SPANDIDOS PUBLICATION: Molecular and Clinical Oncology; Experimental and Therapeutic Medicines	2016- Now 2016- Now

b. Research Proposal
No	Organization	Year
1	DIKTI	2017- Now
3	UNPAD	2017- Now

I. PATENT

No.	Title	No Patent	Years
1.	–
2.

J. BOOK & TEACHING MATERIALS IN THE LAST 5 YEARS

No	Tittles	Press	ISBN	Year
1	Pharmacology on Central Nervous System			2018
2	Pharmacotherapy on Alzheimer’disease			2019
3	Pharmacotherapy on Parkinson’disease			2019