Muharni Muharni, Supriyatna Supriyatna, Husein H. Bahti, Dachriyanus Dachriyanus

Abstract

A phenolic compoud, (-)-epicatechin, was isolated from the stem bark of Garcinia bancana. The structure of this compound was determined base on spectroscopic data such as including UV, IR, 1-D, 2-D NMR, and comparison with the reported data. Biological activity of this compound at free radical scavenging activity by 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) and inhibitory xanthine oxidase(XO) activity showed that (-)- epicathechin active at two methods with IC50 value 8.1 and 8.6 mg/mL respectively.

Keywords: phenolic, (-)-epicatechin, Garcinia bancana, DPPH, XO

Available at http://pdm-mipa.ugm.ac.id/ojs/index.php/ijc/article/view/529Muharni Muharni, Supriyatna Supriyatna, Husein H. Bahti, Dachriyanus Dachriyanus

Abstract

A phenolic compoud, (-)-epicatechin, was isolated from the stem bark of Garcinia bancana. The structure of this compound was determined base on spectroscopic data such as including UV, IR, 1-D, 2-D NMR, and comparison with the reported data. Biological activity of this compound at free radical scavenging activity by 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) and inhibitory xanthine oxidase(XO) activity showed that (-)- epicathechin active at two methods with IC50 value 8.1 and 8.6 mg/mL respectively.

Keywords: phenolic, (-)-epicatechin, Garcinia bancana, DPPH, XO

Available at http://pdm-mipa.ugm.ac.id/ojs/index.php/ijc/article/view/529

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