PHENOLIC COMPOUND FROM THE STEM BARK OF MANGGIS HUTAN (Garcinia bancana Miq.) AND THEIR ANTIOXIDANT ACTIVITYPHENOLIC COMPOUND FROM THE STEM BARK OF MANGGIS HUTAN (Garcinia bancana Miq.) AND THEIR ANTIOXIDANT ACTIVITY

Muharni Muharni, Supriyatna Supriyatna, Husein H. Bahti, Dachriyanus Dachriyanus

Abstract

A phenolic compoud, (-)-epicatechin, was isolated from the stem bark of Garcinia bancana. The structure of this compound was determined base on spectroscopic data such as including UV, IR, 1-D, 2-D NMR, and comparison with the reported data. Biological activity of this compound at free radical scavenging activity by 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) and inhibitory xanthine oxidase(XO) activity showed that (-)- epicathechin active at two methods with IC50 value 8.1 and 8.6 mg/mL respectively.

Keywords: phenolic, (-)-epicatechin, Garcinia bancana, DPPH, XO

Available at http://pdm-mipa.ugm.ac.id/ojs/index.php/ijc/article/view/529Muharni Muharni, Supriyatna Supriyatna, Husein H. Bahti, Dachriyanus Dachriyanus

Abstract

A phenolic compoud, (-)-epicatechin, was isolated from the stem bark of Garcinia bancana. The structure of this compound was determined base on spectroscopic data such as including UV, IR, 1-D, 2-D NMR, and comparison with the reported data. Biological activity of this compound at free radical scavenging activity by 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) and inhibitory xanthine oxidase(XO) activity showed that (-)- epicathechin active at two methods with IC50 value 8.1 and 8.6 mg/mL respectively.

Keywords: phenolic, (-)-epicatechin, Garcinia bancana, DPPH, XO

Available at http://pdm-mipa.ugm.ac.id/ojs/index.php/ijc/article/view/529

Jl. Raya Bandung Sumedang KM 21,
Jatinangor 45363 - Indonesia
Contact Us:
farmasi@unpad.ac.id